What is Cell Cultivation?
Cells used in research and development of regenerative medicine and drug screening are cultured to thrive and proliferate in vitro. To maintain optimal cell conditions during culture, it is considered best to replicate the pre-extraction environment, which requires various procedures and operations.
- Changing culture medium daily
Suctioning and removing old culture medium, without peeling off cells, and adding new culture medium - Conducting cell passages every few days
Uniformly disseminating proliferated cells into multiple culture vessels according to desired size and density
Automated cell culture system that continuously supplies cells
- Changing culture medium daily
Suctioning and removing old culture medium, without peeling off cells, and adding new culture medium - Conducting cell passages every few days
Uniformly disseminating proliferated cells into multiple culture vessels according to desired size and density
Automated cell culture system that continuously supplies cells
Basic Functions for Automating Cell Culturing Processes
Clean cabinet
HEPA filter keeps clean and safe environment equivalent to class II safety cabinet
Refrigerator ＆ Warmer
Refrigerators can store Max. 4 500-mL bottles at 4°C. Warmers are provided to warm liquid temporarily.
Incubator
Max. 60 100-mm dishes (or max. 27 6-well plates) can be stored in CO2 incubator
Cell observation
Deep-learning AI technology leveraged to find cells’ conditions or count cell number
Dispensing & Swinging
Special 10mL pipette is suitable for separating cells. Swing equipment to blend suspension in a dish.
Centrifuging
A centrifuge is implemented for automated cell passage. Considering its effect on cells, it's placed far from the incubator.
Advantages of New System
Automating manual techniques
Reproducing techniques by thoroughly analyzing manual work and utilizing proposed manipulation control technique
Compact size
Achieved a compact size that easily fits into laboratories by designing a structure that is interchangeable with a standard clean bench
Scheduling
Automatically conducting preset movements and maintaining history records of each culture vessel
Specification
Cultivating process | Culture medium change, cell passage, cell observation |
|---|---|
Target cell | Adhesive cell: ES/iPS cell (colony/single cell), etc. |
Heat insulation | 4-500ml bottles |
Culture vessel | Max. 60 Φ100-mm dishes (or max. 27 6-well plates) can be stored |
Dedicated supplies | 10mL pipettes (Max. 100 bottles) |
Cultivation plan | Cultivating process can be set using scheduling function |
Biohazard | Cabinet class II equivalent (Clean 100 equivalent within the unit) |
Decontamination | UV irradiation, peracetic acid fumigation |
Cell observation | Image storage, passage timing determination, cell count |
Main unit dimensions | W 2,000 x D 1,130 x H 2,412 mm |
Utilities |
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